We present a computational evaluation of three hypotheses about sources of deficit in sentence comprehension in aphasia: slowed processing, intermittent deficiency, and resource reduction. The ACT-R based Lewis and Vasishth model is used to implement these three proposals. Slowed processing is implemented as slowed execution time of parse steps; intermittent deficiency as increased random noise in activation of elements in memory; and resource reduction as reduced spreading activation. As data, we considered subject vs. object relative sentences, presented in a self-paced (...) listening modality to 56 individuals with aphasia and 46 matched controls. The participants heard the sentences and carried out a picture verification task to decide on an interpretation of the sentence. These response accuracies are used to identify the best parameters that correspond to the three hypotheses mentioned above. We show that controls have more tightly clustered parameter values than IWA; specifically, compared to controls, among IWA there are more individuals with slow parsing times, high noise, and low spreading activation. We find that individual IWA show differential amounts of deficit along the three dimensions of slowed processing, intermittent deficiency, and resource reduction, overall, there is evidence for all three sources of deficit playing a role, and IWA have a more variable range of parameter values than controls. An important implication is that it may be meaningless to talk about sources of deficit with respect to an abstract verage IWA; the focus should be on the individual's differential degrees of deficit along different dimensions, and on understanding the causes of variability in deficit between participants. (shrink)

"At places distant from where you are, but also uncomfortably close," writes David Takacs, "a holocaust is under way. People are slashing, hacking, bulldozing, burning, poisoning, and otherwise destroying huge swaths of life on Earth at a furious pace." And a cadre of ecologists and conservation biologists has responded, vigorously promoting a new definition of nature: biodiversity --advocating it in Congress and on the Tonight Show; whispering it into the ears of foreign leaders redefining the boundaries of science (...) and politics, ethics and religion, nature and our ideas of nature. These scientists have infused the environmental movement with new focus and direction, but by engaging in such activities, they jeopardize the societal trust that allows them to be public spokespersons for nature in the first place. The Idea of Biodiversity analyzes what biodiversity represents to the biologists who operate in broader society on its behalf, drawing on in-depth interviews with the scientists most active today in the mission to preserve biodiversity, including Peter Raven, Thomas Lovejoy, Jane Lubchenco, and Paul Ehrlich. Takacs explores how and why these biologists shaped the concept of biodiversity and promoted it to society at large--examining their definitions of biodiversity their opinions about spirituality and its role in scientific work the notion of biodiversity as something of intrinsic value and their views on biophilia, E. O. Wilson's idea that humans are genetically predisposed to love nature. Takacs also looks at the work of twentieth-century forerunners of today's conservation biologists--Aldo Leopold, Charles S. Elton, Rachel Carson, David Ehrenfeld--and points out their contributions to the current debates. He takes readers to Costa Rica, where a group of scientists is using biodiversity to remake nature and society. And in an extended section, he profiles the thoughts and work of E. O. Wilson. "When I'm asked, 'should we save this species orthat species, or this place or that place?' the answer is always 'Yes!' with an exclamation point. Because it's obvious. And if you ask me to justify it, then I switch into a more cognitive consciousness and can start giving you reasons, economic reasons, aesthetic reasons. They're all dualistic, in a sense. But the feeling that underlies it is that 'yes!' And that 'yes!' comes out of the affirmation of being part of it all, being part of this whole evolutionary process. And agreeing with Arne Naess that each species, each entity, should be allowed to continue its evolution and to live out its destiny... just do its thing, as we say. Why not? And the 'why not?' is there's too many people."--Michael E. Soule, from an interview in The Idea of Biodiversity "An important contribution, a first distanced examination of a critical, modern topic by a scholarly, honest broker."--E. O. Wilson, Harvard University. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Journal of the History of Philosophy 42.1 (2004) 109-110 [Access article in PDF] Paul Stanistreet. Hume's Scepticism and the Science of Human Nature. Aldershot, England: Ashgate, 2002. Pp.xi + 226. Cloth, $69.95. Any new book on David Hume enters an already overcrowded field. There is no shortage of commentary on Hume's philosophy to be found in a broad range of journals such as Hume Studies, and in (...) recent years a steady stream of monographs and collections have appeared. In addition to this rapidly expanding body of literature, rigorous textual scholarship is being brought to bear on Hume's philosophical writings in the Clarendon edition of Hume's works; significant eighteenth-century editions of Hume are more widely available thanks to facsimile reprints; and a new edition of Hume's correspondence is in preparation. Moreover, this activity has not taken place in a vacuum, insofar as the study of the Scottish Enlightenment and of key figures like Francis Hutcheson, Adam Smith, and Thomas Reid has itself been something of an academic growth industry. Consequently, the interpretation of Hume now requires considerable intellectual expertise, a familiarity with an increasingly technical secondary literature, and a firm grasp on the divergent approaches to Hume that have emerged over the past quarter century.In Hume's Scepticism and the Science of Human Nature, Paul Stanistreet aims both to "provide the reader with an accessible guide to the most significant recent developments in Hume scholarship" and "[defend] a general interpretation of Hume's philosophy" (viii) that is largely based on a close reading of Book I of Hume's A Treatise of Human Nature. Although Stanistreet's introductory statement of his intentions may seem innocuous to the student readership his book is least partly intended for, the apparent innocence of his opening remarks masks a serious issue, namely the validity of grounding a reading of Hume primarily on the first book of the Treatise. A number of leading Hume scholars would argue, pace Stanistreet, that one cannot offer such an interpretation without reference to the two Enquiries and other texts by Hume. Furthermore, Hume himself can be read as opposing Stanistreet's approach. In the face of hostile critics like James Beattie and Thomas Reid, who focussed their attacks on the Treatise, Hume chose to exclude his first publication from the Humean canon and thereby deflect some of the ill-tempered criticism he had been forced to endure in his later years. Thus, in the "Advertisement" prefacing the 1777 edition of the Essays and Treatises on Several Subjects, he explicitly disavowed the Treatise and announced that his philosophical principles were to be found exclusively in the works included in the Essays and Treatises. For the long line of commentators fixated on the Treatise, the "Advertisement" poses questions of interpretation that cannot be ignored, and, for the benefit of his readers, Stanistreet therefore should have not only acknowledged that such questions exist, but also provided some justification for the approach to Hume he adopts.According to Stanistreet, the key to understanding Hume's philosophy is to see how he reconciles his positive programme of constructing a "science of man" with the apparently sceptical thrust of the major arguments advanced in Book I of the Treatise. To show how this reconciliation is achieved, Stanistreet first elucidates Hume's conception of the science of human nature and then proceeds to a detailed consideration of Hume's version of the theory of ideas, his treatment of causation and probable reasoning, and his analysis of our belief in objects external to and independent of ourselves. What emerges from Stanistreet's patient exposition of Hume's position is that Hume was no Pyrrhonian, but rather an advocate for a form of mitigated scepticism that was of a piece with his science of man. For anyone with even a passing familiarity with the Hume literature, this will hardly be a startling conclusion. Nor is it news that Hume was supposedly engaged in establishing a genuinely Newtonian science of the mind, as Stanistreet argues at length in Chapter 1... (shrink)

In this dissertation I put forth a defense of liberalism understood in terms of the principle of state neutrality. In the first half of the dissertation, I attempt to show that a commitment to state neutrality is a central element running through the liberal tradition. I argue for this by examining closely the liberal theories offered by Locke, Mill, Hobhouse, and Rawls. In the second part, I defend liberal neutrality against two prominent criticisms: first, that it is flawed because it (...) cannot acknowledge the importance of certain distinctive virtues needed for a flourishing human life; second, that it fails to account for the importance of civic virtues in citizens and so leads to serious sustainability problems for liberal societies. I conclude that liberal neutrality, properly understood, can withstand both of these criticisms and offers a viable and attractive model of political association. (shrink)

Until the discovery of catalytic RNA, the notion that all enzymes are proteins had seemed incontrovertible. Now the existence of RNA enzymes has been confirmed in a variety of contexts. What is known about the chemistry of RNA‐catalyzed reactions is reviewed below, with particular attention to the self‐splicing rRNA intron of Tetrahymena thermophila and the processing of pre‐tRNA molecules by RNase P.

This study consists of a series of steps toward the development of a general theory of differences in ontological kind. The first part defines the notion of a "logical individual" and argues for its role as the basic ontological unit. I also take issue with those who hold that 'exist' is equivocal, as well as with those who claim that category-mistakes lack a truth-value. This part concludes with the "existence criterion", according to which a thing exists just in case it (...) is a logical individual; examples of things which satisfy and things which fail to satisfy this criterion are discussed. ;The second part covers a number of topics related to the classification of things into kinds. Problems involved in such classification are considered, including a discussion of whether, and on what grounds, certain attributes may be better qualified to define kinds than are others. The idea of ontological kinds is also adumbrated in an intuitive fashion, and a "formalist" strategy for ontological kinds, under which no attribute is treated as more ontologically puissant than any other, is considered and discarded. ;In the last part the ideal of substance is employed as a way of mediating between individuals, on the one hand, and privileged kinds, on the other. Following an examination of substance in Aristotle, six senses of substance are distinguished, of which two are found to hold particular promise for the development of a theory of ontological kinds. Discussion of these two notions of substance includes critiques of "stuff" metaphysics as well as "Aristotelian essentialism". The latter is found to depend on an unwarranted assumption that certain individuals are not only referentially, pragmatically, or psychologically prior to others, but also ontologically privileged. Refutation of this assumption leads to a rehabilitation of Aristotle's notion of "prime matter", but also to a picture of substance closer to Descartes' than to Aristotle's. The arguments against Aristotelian substance finally suggest an account of ontological kinds in terms of the possibility or impossibility of "fusion"--the coinstantiation by two individuals of a single individual concept. (shrink)

Task shifting is increasingly used to address human resource shortages impacting HIV service delivery in low- and middle-income countries. By shifting basic tasks from higher- to lower-trained cadres, such as Community Health Workers, task shifting can reduce overhead costs, improve community outreach, and provide efficient scale-up of essential treatments like antiretroviral therapies. Although there is rich evidence outlining positive outcomes that CHWs bring into HIV programs, important questions remain over their place in service delivery. These challenges often reflect concerns over (...) whether CHWs can mitigate HIV through a means that does not overlook the ethical and practical constraints that undergird their work. Ethical and practical guidance thus needs to become the cornerstone of CHW deployment. This paper analyzes such challenges through the lens of Ethical Principlism. We examined papers identifying substantive and ethical challenges impacting CHWs as they provide HIV services in low- and middle-income contexts. To do this, we analyzed papers written in English and published from year 2000 or later. These articles were identified using MEDLINE, Cochrane Database of Systematic Reviews, and Google Scholar databases. In total, 465 articles were identified, 78 of which met our inclusion criteria. Article reference lists and grey literature were also examined. CHWs experience specific challenges while carrying out their duties, such as conducting emotionally- and physically-demanding tasks with often inadequate training, supervision and compensation. CHWs have also been poorly integrated into health systems, which not only impacts quality of care, but can hinder their prospects for promotion and lead to CHW disempowerment. As we argue, these challenges can be addressed if a set of ethical principles is prioritized, which specifically entail the principles of respect for persons, justice, beneficence, proportionality and cultural humility. CHWs play a crucial role in HIV service delivery, yet the ethical challenges that can accompany their work cannot be overlooked. By prioritizing ethical principles, policymakers and program implementers can better ensure that CHWs are combatting HIV through a means that does not exploit or take their critical role within service delivery for granted. (shrink)

Should a principle of charity be applied to the interpretation of the colour concepts exercised in visual experience? We think not. We shall argue, for one thing, that the grounds for applying a principle of charity are lacking in the case of colour concepts. More importantly, we shall argue that attempts at giving the experience of colour a charitable interpretation either fail to respect obvious features of that experience or fail to interpret it charitably, after all. Charity to visual experience (...) is therefore no motive for resisting the natural, Galilean response to a scientific understanding of light and vision. The best interpretation of colour experience ends up convicting it of widespread and systematic error. (shrink)

This study investigated the relationship between dream emotion and dream character identification. Thirty-five subjects provided 320 dream reports and answers to questions on characters that appeared in their dreams. We found that emotions are almost always evoked by our dream characters and that they are often used as a basis for identifying them. We found that affection and joy were commonly associated with known characters and were used to identify them even when these emotional attributes were inconsistent with those of (...) the waking state. These findings are consistent with the finding that the dorsolateral prefrontal cortex, associated with short-term memory, is less active in the dreaming compared to the wake brain, while the paleocortical and subcortical limbic areas are more active. The findings are also consistent with the suggestion that these limbic areas have minimal input from the dorsolateral prefrontal cortex in the dreaming brain. (shrink)

The dispute between realists about color and anti-realists is actually a dispute about the nature of color properties. The disputants do not disagree over what material objects are like. Rather, they disagree over whether any of the uncontroversial facts about material objects--their powers to cause visual experiences, their dispositions to reflect incident light, their atomic makeup, and so on--amount to their having colors. The disagreement is thus about which properties colors are and, in particular, whether colors are any of the (...) properties in a particular set that is acknowledged on both sides to exhaust the properties of material objects. In a previous paper we discussed at length one attempt to identify colors with particular properties of material objects--namely, with their dispositions to cause visual experiences. Here we shall discuss a different and perhaps more influential version of realism, which says that the colors of material objects are microphysical properties of their surfaces. We shall call this theory physicalism about color (physicalism, for short). In order to evaluate this theory, however, we shall first have to clarify some methodological issues. Our hope is that we can bring some further clarity to the question of color realism, whether or not we succeed in our critique of the physicalists' answer. (shrink)

We present data and argument to show that in Tetris - a real-time interactive video game - certain cognitive and perceptual problems are more quickly, easily, and reliably solved by performing actions in the world rather than by performing computational actions in the head alone. We have found that some translations and rotations are best understood as using the world to improve cognition. These actions are not used to implement a plan, or to implement a reaction; they are used to (...) change the world in order to simplify the problem-solving task. Thus, we distinguish pragmatic actions ñ actions performed to bring one physically closer to a goal - from epistemic actions - actions performed to uncover information that is hidden or hard to compute mentally. To illustrate the need for epistemic actions, we first develop a standard information-processing model of Tetris-cognition, and show that it cannot explain performance data from human players of the game - even when we relax the assumption of fully sequential processing. Standard models disregard many actions taken by players because they appear unmotivated or superfluous. However, we describe many such actions that are actually taken by players that are far from superfluous, and that play valuable roles in improving human performance. We argue that traditional accounts are limited because they regard action as having a single function: to change the world. By recognizing a second function of action - an epistemic function - we can explain many of the actions that a traditional model cannot. Although, our argument is supported by numerous examples specifically from Tetris, we outline how the one category of epistemic action can be incorporated into theories of action more generally. (shrink)

We say that a sentence A is a permissive consequence of a set X of premises whenever, if all the premises of X hold up to some standard, then A holds to some weaker standard. In this paper, we focus on a three-valued version of this notion, which we call strict-to-tolerant consequence, and discuss its fruitfulness toward a unified treatment of the paradoxes of vagueness and self-referential truth. For vagueness, st-consequence supports the principle of tolerance; for truth, it supports the (...) requisite of transparency. Permissive consequence is non-transitive, however, but this feature is argued to be an essential component to the understanding of paradoxical reasoning in cases involving vagueness or self-reference. (shrink)

Paul Ricoeur was one of the foremost interpreters and translators of Edmund Husserl's philosophy. These nine essays present Ricoeur's interpretation of the most important of Husserl's writings, with emphasis on his philosophy of consciousness rather than his work in logic. In Ricoeur's philosophy, phenomenology and existentialism came of age and these essays provide an introduction to the Husserlian elements which most heavily influenced his own philosophical position.

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Die Leitgedanken meiner Untersuchungen über die Grundlagen der Mathematik, die ich - anknüpfend an frühere Ansätze - seit 1917 in Besprechungen mit P. BERNAYS wieder aufgenommen habe, sind von mir an verschiedenen Stellen eingehend dargelegt worden. Diesen Untersuchungen, an denen auch W. ACKERMANN beteiligt ist, haben sich seither noch verschiedene Mathematiker angeschlossen. Der hier in seinem ersten Teil vorliegende, von BERNAYS abgefaßte und noch fortzusetzende Lehrgang bezweckt eine Darstellung der Theorie nach ihren heutigen Ergebnissen. Dieser Ergebnisstand weist zugleich die Richtung (...) für die weitere Forschung in der Beweistheorie auf das Endziel hin, unsere üblichen Methoden der Mathematik samt und sonders als widerspruchsfrei zu erkennen. Im Hinblick auf dieses Ziel möchte ich hervorheben, daß die zeit weilig aufgekommene Meinung, aus gewissen neueren Ergebnissen von GÖDEL folge die Undurchführbarkeit meiner Beweistheorie, als irrtüm lich erwiesen ist. Jenes Ergebnis zeigt in der Tat auch nur, daß man für die weitergehenden Widerspruchsfreiheitsbeweise den finiten Stand punkt in einer schärferen Weise ausnutzen muß, als dieses bei der Be trachtung der elementaren Formallsmen erforderlich ist. Göttingen, im März 1934 HILBERT Vorwort zur ersten Auflage Eine Darstellung der Beweistheorie, welche aus dem HILBERTschen Ansatz zur Behandlung der mathematisch-logischen Grundlagenpro bleme erwachsen ist, wurde schon seit längerem von HILBERT ange kündigt. (shrink)

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind. Der Verlag stellt mit diesem Archiv Quellen für die historische wie auch die disziplingeschichtliche Forschung zur Verfügung, die jeweils im historischen Kontext betrachtet werden müssen. Dieser Titel erschien in der Zeit vor 1945 und wird daher in seiner zeittypischen politisch-ideologischen Ausrichtung vom Verlag nicht beworben.

There is growing interest among pharmaceutical policymakers in how to “disinvest” from subsidized medicines. This is due to both the rapidly rising costs of healthcare and the increasing use of accelerated and conditional reimbursement pathways which mean that medicines are being subsidized on the basis of less robust evidence of safety and efficacy. It is crucial that disinvestment decisions are morally sound and socially legitimate, but there is currently no framework to facilitate this. We therefore reviewed the bioethics literature in (...) order to identify ethical principles and concepts that might be relevant to pharmaceutical disinvestment decisions. This revealed a number of key ethical considerations—both procedural and substantive—that need to be considered when making pharmaceutical disinvestment decisions. These principles do not, however, provide practical guidance so we present a framework outlining how they might be applied to different types of disinvestment decisions. We also argue that, in this context, even the most rigorous ethical reasoning is likely to be overridden by moral intuitions and psychological biases and that disinvestment decisions will need to strike the right balance between respecting justifiable moral intuitions and overriding unjustifiable psychological impulses. (shrink)

This paper describes DIVA (Dynamic Imagery for Visual Analogy), a computational model of visual imagery based on the scene graph, a powerful representational structure widely used in computer graphics. Scene graphs make possible the visual display of complex objects, including the motions of individual objects. Our model combines a semantic-network memory system with computational procedures based on scene graphs. The model can account for people’s ability to produce visual images of moving objects, in particular the ability to use dynamic visual (...) analogies that compare two systems of objects in motion. (shrink)

Edited by Thomas A. Shannon, this series provides anthologies of critical essays and reflections by leading ethicists in four pivotal areas: reproductive technologies, genetic technologies, death and dying, and health care policy. The goal of this series is twofold: first, to provide a set of readers on thematic topics for introductory or survey courses in bioethics or for courses with a particular theme or time limitation. Second, each of the readers in this series is designed to help students focus more (...) thoroughly and effectively on specific topics that flesh out the ethical issues at the core of bioethics. The series is also highly accessible to general readers interested in bioethics. (shrink)

Extant theoretical work on the political resource curse implies that dependence on resource revenues should decrease autocracies’ likelihood of democratizing but not necessarily affect democracies’ chances of survival. Yet most previous empirical studies estimate models that are ill-suited to address this claim. We improve upon earlier studies, estimating a dynamic logit model that interacts a continuous measure of resource dependence with an indicator of regime type using data from 166 countries, covering the period from 1816-2006. We find that an increase (...) in resource dependence at time t - 1 increases the likelihood of autocratic persistence at t, but has no appreciable effect on democratic survival. We go beyond existing empirical studies to show that increases in resource dependence have persistent and substantial cumulative effects on autocracies' likelihood of becoming democratic over the long-term, showing that the total effect of resource dependence on regime type is much larger than the short-term (one period) effect indicates. (shrink)

The material contained in the following translation was given in substance by Professor Hilbertas a course of lectures on euclidean geometry at the University of G]ottingen during the wintersemester of 1898-1899. The results of his investigation were re-arranged and put into the formin which they appear here as a memorial address published in connection with the celebration atthe unveiling of the Gauss-Weber monument at G]ottingen, in June, 1899. In the French edition, which appeared soon after, Professor Hilbert made some additions, (...) particularly in the concludingremarks, where he gave an account of the results of a recent investigation made by Dr. Dehn.These additions have been incorporated in the following translation.Geometry, like arithmetic, requires for its logical development only a small number ofsimple, fundamental principles. These fundamental principles are called the axioms ofgeometry. The choice of the axioms and the investigation of their relations to one anotheris a problem which, since the time of Euclid, has been discussed in numerous excellentmemoirs to be found in the mathematical literature.1 This problem is tantamount to thelogical analysis of our intuition of space. (shrink)